Exposing the veiled truths about Lynch Syndrome
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lynch syndrome Many people remain unaware of Lynch syndrome and the important role genetic screening can play in cancer prevention and early detection. This article explores the key facts about Lynch syndrome that everyone should understand. 5 Things Everyone Should Know About Lynch Syndrome What is Lynch Syndrome? Lynch syndrome, also known as hereditary nonpolyposis colorectal cancer (HNPCC), is an inherited disorder caused by mutations in DNA mismatch repair genes. These genes normally help repair damaged DNA, but mutations disrupt this process and allow errors to accumulate. This dramatically elevates risks for certain cancers to develop. Cancer Risks Individuals with Lynch syndrome have a high lifetime risk of developing colorectal cancer, endometrial cancer, ovarian cancer, stomach cancer, urinary tract cancer, small intestine cancer, and other malignancies. Colorectal cancer risk may be as high as 80% for women and 60% for men by age 70-75 without screening. The risk of endometr...